The Iditarod Trail Commitee have just released the first of mushers lined up for the 2021 race from Anchorage to Nome.
| Entrant # | Musher Name | Sex | City | State | Country | Status |
|---|---|---|---|---|---|---|
| 1 | Paige Drobny | F | Cantwell | AK | USA | Veteran |
| 2 | Jason Campeau | M | Rocky Mountain House | AB | CANADA | Veteran |
| 3 | Jennifer Campeau | F | Alberta | Canada | Rookie | |
| 4 | Martin Buser | M | Big Lake | AK | USA | Veteran |
| 5 | Riley Dyche | M | Fairbanks | AK | USA | Veteran |
| 6 | Dan Kaduce | M | Chatanika | AK | USA | Veteran |
| 7 | Ryne Olson | F | Two Rivers | AK | USA | Veteran |
| 8 | Sebastien Dos Santos Borges | M | Chazey-Bons | France | Rookie | |
| 9 | Joanna Jagow | F | Fairbanks | AK | Rookie | |
| 10 | Dennis Kananowicz | M | Tolsona | AK | USA | Veteran |
| 11 | Jeff Deeter | M | Fairbanks | AK | USA | Veteran |
| 12 | Michelle Phillips | F | Tagish | YT | CANADA | Veteran |
| 13 | Matt Hall | M | Two Rivers | AK | USA | Veteran |
| 14 | Ryan Redington | M | Skagway | AK | USA | Veteran |
| 15 | Gunnar Johnson | M | Duluth | MN | USA | Veteran |
| 16 | Brent Sass | M | Eureka | AK | USA | Veteran |
| 17 | Linwood Fiedler | M | Willow | AK | USA | Veteran |
| 18 | Marcelle Fressineau | F | Whitehorse | YT | CANADA | Veteran |
| 19 | Karin Hendrickson | F | Wasilla | AK | USA | Veteran |
| 20 | Lev Shvarts | M | Willow | AK | USA | Veteran |
| 21 | Wade Marrs | M | Willow | AK | USA | Veteran |
| 22 | Jeff King | M | Denali Park | AK | USA | Veteran |
| 23 | Aaron Peck | M | Grande Prairie | AB | CANADA | Veteran |
| 24 | Nicolas Petit | M | Girdwood | AK | USA | Veteran |
| 25 | Josi Thyr | F | Olney | Montana | Rookie | |
| 26 | Gabe Dunham | F | Willow | AK | USA | Rookie |
| 27 | Cody Strathe | M | Fairbanks | AK | USA | Veteran |
| 28 | Susannah Tuminelli | F | Willow | AK | Rookie | |
| 29 | Mats Pettersson | M | Kiruna | SWEDEN | Veteran | |
| 30 | Will Troshynski | M | Fairbanks | Alaska | United States | Rookie |
| 31 | Chad Stoddard | M | Anchorage | Alaska | United States | Rookie |
| 32 | Ramey Smyth | M | Willow | AK | USA | Veteran |
| 33 | Anna Berington | F | Knik | AK | USA | Veteran |
| 34 | Kristy Berington | F | Knik | AK | USA | Veteran |
| 35 | Christopher Parker | M | Fairbanks | Alaska | United States | Rookie |
| 36 | Thomas Waerner | M | Torpa | NORWAY | Veteran | |
| 37 | Dakota Schlosser | M | Willow | Alaska | Rookie | |
| 38 | Aaron Burmeister | M | Nome/Nenana | AK | USA | Veteran |
| 39 | Hal Hanson | M | Kenai | AK | Rookie | |
| 40 | Dallas Seavey | M | Talkeetna | AK | USA | Veteran |
| 41 | Jessie Royer | F | Fairbanks | AK | USA | Veteran |
| 42 | Richie Diehl | M | Aniak | AK | USA | Veteran |
| 43 | Joar Leifseth Ulsom | M | Mo i Rana | NORWAY | Veteran | |
| 44 | Paul Gebhardt | M | Kasilof | AK | USA | Veteran |
| 45 | Shaynee Traska | F | Gladwin | MI | USA | Veteran |
| 46 | Peter Kaiser | M | Bethel | AK | USA | Veteran |
| 47 | Brett Bruggeman | M | Great Falls | MT | USA | Veteran |
| 48 | Matthew Failor | M | Willow | AK | USA | Veteran |
| 49 | Aliy Zirkle | F | Two Rivers | AK | USA | Veteran |
| 50 | Travis Beals | M | Seward | AK | USA | Veteran |
| 51 | Alan Eischens | M | Wasilla | AK | USA | Veteran |
| 52 | Sean Williams | M | Chugiak | AK | US | Rookie |
| 53 | Joshua McNeal | M | Fairbanks | AK | US | Rookie |
| 54 | Mille Porsild | F | DENMARK | Veteran | ||
| 55 | Severin Cathry | M | Switzerland | Rookie | ||
| 56 | Quince Mountain | M | Mountain | WI | USA | Rookie |
| 57 | Sarah Stokey | F | Seward | AK | USA | Veteran |
| 58 | Brenda Mackey | F | Two Rivers | AK | US | Rookie |
